Cognitive dysfunction in corticobasal degeneration
نویسندگان
چکیده
منابع مشابه
Cognitive dysfunction in corticobasal degeneration.
Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings. In addition, pathophysiological findings and the molecular basis have been delineated and several aspects of its cognitive manifestations have been clarified. Thus, not...
متن کاملCognitive and motor assessment in autopsy-proven corticobasal degeneration.
OBJECTIVE To investigate the clinical features of autopsy-proven corticobasal degeneration (CBD). METHODS We evaluated symptoms, signs, and neuropsychological deficits longitudinally in 15 patients with autopsy-proven CBD and related these observations directly to the neuroanatomic distribution of disease. RESULTS At presentation, a specific pattern of cognitive impairment was evident, wher...
متن کاملCorticobasal degeneration.
Corticobasal degeneration is a progressive neurodegenerative disease that typically presents with asymmetrical parkinsonism and cognitive dysfunction. Recent molecular advances have given some clues to the pathogenesis of the disease. Clinical diagnosis is complicated by both the variability of presentation of true corticobasal degeneration, for example as a dementing illness, and the syndromes...
متن کاملCorticobasal degeneration
75 Introduction and history While historical review suggests earlier reports of the entity now known as corticobasal degeneration (CBD), the disease was fi rst clearly described in a series of three cases in 1968, when it was termed corticodentatonigral degeneration with neuronal achromasia [ 1 ]. Subsequent terminology has included corticonigral degeneration with neuronal achromasia [ 2 ], cor...
متن کاملQuantifier comprehension in corticobasal degeneration.
In this study, we investigated patients with focal neurodegenerative diseases to examine a formal linguistic distinction between classes of generalized quantifiers, like "some X" and "less than half of X." Our model of quantifier comprehension proposes that number knowledge is required to understand both first-order and higher-order quantifiers. The present results demonstrate that corticobasal...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2017
ISSN: 0004-282X
DOI: 10.1590/0004-282x20170077